期刊
CHILD DEVELOPMENT
卷 81, 期 1, 页码 166-182出版社
WILEY-BLACKWELL PUBLISHING, INC
DOI: 10.1111/j.1467-8624.2009.01387.x
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资金
- MRC [G0500079, G19/2, G0500870] Funding Source: UKRI
- Medical Research Council [G9817803B] Funding Source: researchfish
- Medical Research Council [G0500079(73692), G0500079, G0500870, G19/2] Funding Source: Medline
- Autism Speaks [AS1650] Funding Source: Medline
Prenatal and neonatal events were reported by parents of 13,690 eighteen-month-old twins enrolled in the Twins Early Development Study, a representative community sample born in England and Wales. At ages 7-8, parents and teachers completed questionnaires on social and nonsocial autistic-like features and parents completed the Childhood Asperger Syndrome Test. Correlations between prenatal and neonatal events and autistic-like features were weak, both in the whole sample (r = .00-.07) and at the 5% quantitative extreme (phenotypic group correlations = .01-.11), after controlling for socioeconomic status and cognitive ability. Neonatal problems showed modest heritability (13%-14%) and significant shared and nonshared environmental influences (55%-59% and 28%-31%, respectively). Differences in identical twins' neonatal problems correlated weakly with their difference scores on autistic-like features (r = .01-.06).
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