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Douglas Hanahan et al.
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Vittorio Calabrese et al.
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Aaron T. Jacobs et al.
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Victoria A. Johnson et al.
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Suryakant K. Niture et al.
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Mikko Taipale et al.
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Young-Hoon Ahn et al.
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Jane Trepel et al.
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Andrew Vila et al.
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Christopher R. Williams et al.
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DL Carbone et al.
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A Martínez-Ruiz et al.
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Regulation of p53 stability and p53-dependent apoptosis by NADH quinone oxidoreductase-1
G Asher et al.
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G Nardai et al.
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MG Marcu et al.
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