相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。MDM2, MDMX and p53 in oncogenesis and cancer therapy
Mark Wade et al.
NATURE REVIEWS CANCER (2013)
Surf the Post-translational Modification Network of p53 Regulation
Bo Gu et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2012)
Histone deacetylase inhibitors enhance the anticancer activity of nutlin-3 and induce p53 hyperacetylation and downregulation of MDM2 and MDM4 gene expression
Chithra D. Palani et al.
INVESTIGATIONAL NEW DRUGS (2012)
P53-dependent antiproliferative and pro-apoptotic effects of trichostatin A (TSA) in glioblastoma cells
K. Bajbouj et al.
JOURNAL OF NEURO-ONCOLOGY (2012)
Epigenetic protein families: a new frontier for drug discovery
Cheryl H. Arrowsmith et al.
NATURE REVIEWS DRUG DISCOVERY (2012)
Dynamically regulated sumoylation of HDAC2 controls p53 deacetylation and restricts apoptosis following genotoxic stress
Andre Brandl et al.
JOURNAL OF MOLECULAR CELL BIOLOGY (2012)
Proteasome Inhibitors Induce p53-Independent Apoptosis in Human Cancer Cells
Bulbul Pandit et al.
AMERICAN JOURNAL OF PATHOLOGY (2011)
Sirtuin 1 in malignant transformation: Friend or foe?
Yujiang Fang et al.
CANCER LETTERS (2011)
NF-κB addiction and its role in cancer: 'one size does not fit all'
M. M. Chaturvedi et al.
ONCOGENE (2011)
Histone deacetylase inhibitors prime medulloblastoma cells for chemotherapy-induced apoptosis by enhancing p53-dependent Bax activation
S. Haecker et al.
ONCOGENE (2011)
A decade of exploring the cancer epigenome - biological and translational implications
Stephen B. Baylin et al.
NATURE REVIEWS CANCER (2011)
Inhibitors of HDACs - Effective Drugs Against Cancer?
S. Mueller et al.
CURRENT CANCER DRUG TARGETS (2010)
Chemical phylogenetics of histone deacetylases
James E. Bradner et al.
NATURE CHEMICAL BIOLOGY (2010)
The C terminus of p53 binds the N-terminal domain of MDM2
Masha V. Poyurovsky et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)
The histone deacetylase inhibitors LAQ824 and LBH589 do not require death receptor signaling or a functional apoptosome to mediate tumor cell death or therapeutic efficacy
Leigh Ellis et al.
BLOOD (2009)
Blinded by the Light: The Growing Complexity of p53
Karen H. Vousden et al.
CELL (2009)
Rational Combinations Using HDAC Inhibitors
Michael Bots et al.
CLINICAL CANCER RESEARCH (2009)
Inhibitors of histone deacetylase (HDAC) restore the p53 pathway in neuroblastoma cells
F. Condorelli et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator
Sonia Lain et al.
CANCER CELL (2008)
Directing cancer cells to self-destruct with pro-apoptotic receptor agonists
Avi Ashkenazi
NATURE REVIEWS DRUG DISCOVERY (2008)
Small molecule obatoclax (GX15-070) antagonizes MCL-1 and overcomes MCL-1-mediated resistance to apoptosis
Mai Nguyen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Analysis of the apoptotic and therapeutic activities of histone deacetylase inhibitors by using a mouse model of B cell lymphoma
R. K. Lindemann et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
A coordinated action of Bax, PUMA, and p53 promotes MG132-induced mitochondria activation and apoptosis in colon cancer cells
Wen-Xing Ding et al.
MOLECULAR CANCER THERAPEUTICS (2007)
Acetylation of p53 at lysine 373/382 by the histone deacetylase inhibitor depsipeptide induces expression of p21Waf1/Cip1
Y Zhao et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Histone deacetylase inhibitors require caspase activity to induce apoptosis in lung and prostate carcinoma cells
H Sonnemann et al.
CANCER LETTERS (2006)
Histone deacetylase inhibitor-mediated radiosensitization of human cancer cells: Class differences and the potential influence of p53
IA Kim et al.
CLINICAL CANCER RESEARCH (2006)
Role of p53 status in chemosensitivity determination of cancer cells against histone deacetylase inhibitor sodium butyrate
J Joseph et al.
INTERNATIONAL JOURNAL OF CANCER (2005)
Do inducers of apoptosis trigger caspase-independent cell death?
JE Chipuk et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)
Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway
A Insinga et al.
NATURE MEDICINE (2005)
Role of caspases, bid, and p53 in the apoptotic response triggered by histone deacetylase inhibitors trichostatin-A (TSA) suberoylanilide hydroxamic acid and (SAHA)
C Henderson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
TRAIL-induced apoptosis requires Bax-dependent mitochondria release of Smac/DIABLO
YB Deng et al.
GENES & DEVELOPMENT (2002)
Tumor-cell resistance to death receptor-induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax
H LeBlanc et al.
NATURE MEDICINE (2002)
The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species
AA Ruefli et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Activation of the p21WAF1/CIP1 promoter independent of p53 by the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) through the Sp1 sites
LL Huang et al.
ONCOGENE (2000)