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S. E. Rivkin et al.
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Xiao-Feng Le et al.
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G. Brockhoff et al.
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Peter Mullen et al.
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Clinical activity of Pertuzumab (rhuMAb 2C4), a HER dimerization inhibitor, in advanced ovarian cancer: Potential predictive relationship with tumor HER2 activation status
Michael S. Gordon et al.
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Alberto Serrano-Olvera et al.
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L Arnould et al.
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2C4, a monoclonal antibody against HER2, disrupts the HER kinase signaling pathway and inhibits ovarian carcinoma cell growth
N Takai et al.
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KK Zorn et al.
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RT Marquez et al.
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HA Burris et al.
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XF Le et al.
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XF Le et al.
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Human kallikrein gene 11 (KLK11) mRNA overexpression is associated with poor prognosis in patients with epithelial ovarian cancer
K Shigemasa et al.
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R Nahta et al.
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MC Franklin et al.
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P27kip1 down-regulation is associated with trastuzumab resistance in breast cancer cells
R Nahta et al.
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G2/M arrest by 1,25-dihydroxyvitamin D3 in ovarian cancer cells mediated through the induction of GADD45 via an exonic enhancer
F Jiang et al.
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MA Bookman et al.
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RL Camp et al.
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DB Agus et al.
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VG Tusher et al.
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RA Clynes et al.
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