期刊
BRITISH JOURNAL OF CANCER
卷 103, 期 1, 页码 136-142出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/sj.bjc.6605732
关键词
childhood cancer; socioeconomic status; epidemiology
类别
资金
- NCI NIH HHS [T32 CA099936] Funding Source: Medline
BACKGROUND: Little has been reported on socioeconomic (SES) patterns of risk for most forms of childhood cancer. METHODS: Population-based case-control data from epidemiological studies of childhood cancer conducted in five US states were pooled and associations of maternal, paternal and household educational attainment with childhood cancers were analysed. Odds ratios (ORs) and 95% confidence intervals were estimated using logistic regression, controlling for confounders. RESULTS: Although there was no association with parental education for the majority of cancers evaluated, there was an indication of a positive association with lower education for Hodgkin's and Burkitt's lymphoma and Wilm's tumour, with the ORs ranging from 1.5 to > 3.0 times that of more educated parents. A possible protective effect was seen for lower parental education and astrocytoma and hepatoblastoma, with ORs reduced by 30 to 40%. CONCLUSIONS: These study results should be viewed as exploratory because of the broad nature of the SES assessment, but they give some indication that childhood cancer studies might benefit from a more thorough assessment of SES. British Journal of Cancer (2010) 103, 136-142. doi:10.1038/sj.bjc.6605732 www.bjcancer.com Published online 8 June 2010 (C) 2010 Cancer Research UK
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