EBV-associated gastric carcinoma in high- and low-incidence areas for nasopharyngeal carcinoma

BACKGROUND: Approximately 10% of gastric carcinomas are associated with Epstein-Barr virus (EBV). The Inuit in Greenland have a high incidence of EBV-associated nasopharyngeal carcinoma. METHODS: We conducted a population-based case-control study comparing gastric carcinomas in Greenland and in Denmark. RESULTS: The prevalence rate of EBV-associated gastric carcinomas was 8.5% in both populations. CONCLUSION: The findings of this study argue against a general susceptibility to EBV-associated carcinomas among the Inuit. British Journal of Cancer (2009) 101, 530-533. doi:10.1038/sj.bjc.6605168 www.bjcancer.com Published online 14 July 2009 (C) 2009 Cancer Research UK