Vegetable, fruit and antioxidant nutrient consumption and subsequent risk of hepatocellular carcinoma: a prospective cohort study in Japan

In a population-based prospective study of 19 998 Japanese individuals, consumption of vegetables, green-yellow and green leafy vegetables was inversely associated with the risk of hepatocellular carcinoma (101 cases), with multivariable hazard ratios for the highest vs lowest tertile of 0.61 (95% confidence interval (CI) 0.36-1.03, P-trend = 0.07), 0.65 (95% CI = 0.39-1.08, P-trend = 0.06) and 0.59 (95% CI = 0.35-1.01, P-trend = 0.04), respectively.