期刊
BRIEFINGS IN FUNCTIONAL GENOMICS
卷 9, 期 5-6, 页码 416-423出版社
OXFORD UNIV PRESS
DOI: 10.1093/bfgp/elq031
关键词
RADSeq; population genetics; next-generation sequencing; genetic marker discovery; SNP discovery
资金
- Medical Research Council [MRC G0900740]
- Natural Environmental Research Council in the UK [NERC R8/H10/56]
- Biotechnology and Biological Sciences Research Council [BB/F021135/1] Funding Source: researchfish
- Medical Research Council [G0900740] Funding Source: researchfish
- Natural Environment Research Council [NBAF010003] Funding Source: researchfish
- BBSRC [BB/F021135/1] Funding Source: UKRI
- MRC [G0900740] Funding Source: UKRI
- NERC [NBAF010003] Funding Source: UKRI
Next-generation sequencing technologies are making a substantial impact on many areas of biology, including the analysis of genetic diversity in populations. However, genome-scale population genetic studies have been accessible only to well-funded model systems. Restriction-site associated DNA sequencing, a method that samples at reduced complexity across target genomes, promises to deliver high resolution population genomic data-thousands of sequenced markers across many individuals-for any organism at reasonable costs. It has found application in wild populations and non-traditional study species, and promises to become an important technology for ecological population genomics.
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