期刊
BRIEFINGS IN BIOINFORMATICS
卷 15, 期 4, 页码 637-647出版社
OXFORD UNIV PRESS
DOI: 10.1093/bib/bbs088
关键词
MapReduce; bioinformatics; Hadoop
资金
- Natural Science Foundation of China [61001013, 61102136, 61100032]
- Natural Science Foundation of Fujian Province of China [2011J05158]
- Fundamental Research Funds for the Central Universities of China [2011121049, 2010121072]
Bioinformatics is challenged by the fact that traditional analysis tools have difficulty in processing large-scale data from high-throughput sequencing. The open source Apache Hadoop project, which adopts the MapReduce framework and a distributed file system, has recently given bioinformatics researchers an opportunity to achieve scalable, efficient and reliable computing performance on Linux clusters and on cloud computing services. In this article, we present MapReduce frame-based applications that can be employed in the next-generation sequencing and other biological domains. In addition, we discuss the challenges faced by this field as well as the future works on parallel computing in bioinformatics.
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