期刊
BRIEFINGS IN BIOINFORMATICS
卷 10, 期 4, 页码 392-407出版社
OXFORD UNIV PRESS
DOI: 10.1093/bib/bbp024
关键词
knowledge management; system biology; Semantic Web; ontology; data integration; knowledge representation
New knowledge is produced at a continuously increasing speed, and the list of papers, databases and other knowledge sources that a researcher in the life sciences needs to cope with is actually turning into a problem rather than an asset. The adequate management of knowledge is therefore becoming fundamentally important for life scientists, especially if they work with approaches that thoroughly depend on knowledge integration, such as systems biology. Several initiatives to organize biological knowledge sources into a readily exploitable resourceome are presently being carried out. Ontologies and Semantic Web technologies revolutionize these efforts. Here, we review the benefits, trends, current possibilities, and the potential this holds for the biosciences.
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