期刊
HUMAN NATURE-AN INTERDISCIPLINARY BIOSOCIAL PERSPECTIVE
卷 21, 期 1, 页码 19-38出版社
SPRINGER
DOI: 10.1007/s12110-010-9078-0
关键词
Health disparities; Aging; Stress; Race/ethnicity; Weathering; Women's health; Poverty; Telomeres
资金
- EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT [R24HD041028] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF NURSING RESEARCH [U01NR004061] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE ON AGING [T32AG000221, U01AG017719, P30AG012846, P20AG012846, R01AG032632] Funding Source: NIH RePORTER
- NIA NIH HHS [P30 AG012846, R01 AG032632, R01 AG032632-01A1, U01 AG017719, T32 AG000221-18, R01 AG032632-02, P30 AG012846-15, T32 AG000221, P20 AG012846] Funding Source: Medline
- NICHD NIH HHS [R24 HD041028] Funding Source: Medline
- NINR NIH HHS [U01 NR004061] Funding Source: Medline
We hypothesize that black women experience accelerated biological aging in response to repeated or prolonged adaptation to subjective and objective stressors. Drawing on stress physiology and ethnographic, social science, and public health literature, we lay out the rationale for this hypothesis. We also perform a first population-based test of its plausibility, focusing on telomere length, a biomeasure of aging that may be shortened by stressors. Analyzing data from the Study of Women's Health Across the Nation (SWAN), we estimate that at ages 49-55, black women are 7.5 years biologically older than white women. Indicators of perceived stress and poverty account for 27% of this difference. Data limitations preclude assessing objective stressors and also result in imprecise estimates, limiting our ability to draw firm inferences. Further investigation of black-white differences in telomere length using large-population-based samples of broad age range and with detailed measures of environmental stressors is merited.
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