期刊
BRAIN RESEARCH REVIEWS
卷 57, 期 1, 页码 125-133出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.brainresrev.2007.08.004
关键词
modular organization; spinal cord; muscle synergies; factorization algorithms
资金
- NIGMS NIH HHS [T32 GM007484-22] Funding Source: Medline
- NINDS NIH HHS [P01 NS044393-020002] Funding Source: Medline
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [T32GM007484] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE [P01NS044393] Funding Source: NIH RePORTER
We review experiments supporting the hypothesis that the vertebrate motor system produces movements by combining a small number of units of motor output. Using a variety of approaches such as microstimulation of the spinal cord, NMDA iontophoresis, and an examination of natural behaviors in intact and deafferented animals we have provided evidence for a modular organization of the spinal cord. A module is a functional unit in the spinal cord that generates a specific motor output by imposing a specific pattern of muscle activation. Such an organization might help to simplify the production of movements by reducing the degrees of freedom that need to be specified. (c) 2007 Elsevier B.V. All rights reserved.
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