期刊
BRAIN RESEARCH
卷 1554, 期 -, 页码 49-58出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.brainres.2014.01.043
关键词
Sympathetic activity; Emotional stress; Dorsomedial hypothalamus; Cardiac arrythmias
资金
- CNPq [301519/2009-9, 472614/2011-8]
- FAPEMIG [APQ-01097-11]
- CAPES
Maintenance of homeostasis in normal or stressful situations depends upon mechanisms controlling autonomic activity. Central requirement for changes in sympathetic output resulting from emotional stress must be adjusted to the input signals from visceral sensory afferent (feedback response) for an optimum cardiovascular performance. There is a large body of evidence indicating that emotional stress can lead to cardiovascular disease. Reviewing the descending pathways from dorsomedial hypothalamus, a key region involved in the cardiovascular response to emotional stress, we discuss the interactions between mechanisms controlling the sympathetic output to the cardiovascular system and the possible implications in cardiovascular disease. (C) 2014 Elsevier B.V. All rights reserved.
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