4.5 Review

Recent advances in optogenetics and pharmacogenetics

期刊

BRAIN RESEARCH
卷 1511, 期 -, 页码 1-5

出版社

ELSEVIER
DOI: 10.1016/j.brainres.2013.01.026

关键词

Optogenetics; Pharmacogenetics; Channelrhodopsin; DREADD; Designer receptor; Viral transduction; Neurotransmitter signaling; Motivation/cognition; Autonomic function; Sensory function; Translational neuroscience

资金

  1. Howard Hughes Medical Institute Funding Source: Medline
  2. NIDA NIH HHS [R37 DA006214, P50 DA015369, R21 DA025837] Funding Source: Medline
  3. NIMH NIH HHS [R21 MH099534, R01 MH092868] Funding Source: Medline

向作者/读者索取更多资源

Optogenetics with microbial opsin genes, and pharmacogenetics with designer receptors, represent potent and versatile experimental modalities that can be integrated with each other as well as with a rich diversity of synergistic methods to provide fundamental opportunities in neuroscience research. The 7th Annual Brain Research Meeting in New Orleans in October 2012, Optogenetics and Pharmacogenetics in Neuronal Function and Dysfunction, brought together leading researchers that have developed and used these tools to explore a wide range of questions in nervous system function and dysfunction. This special issue of Brain Research includes articles by speakers in this meeting and others, which together synthesize and summarize the state of the art for optogenetics and designer receptors. This article is part of a Special Issue entitled Optogenetics (7th BRES) (C) 2013 Elsevier B.V. All rights reserved.

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