期刊
BRAIN RESEARCH
卷 1383, 期 -, 页码 242-251出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.brainres.2011.01.090
关键词
Hemodynamics; Near-infrared spectroscopy; Preschool child; Occipital cortex; Vision
资金
- Knowledge Cluster Initiative from the Japanese Ministry of Education, Culture, Sports, Science and Technology
- JSPS [40467098]
- Grants-in-Aid for Scientific Research [22653077, 22330204] Funding Source: KAKEN
In this study we used near-infrared spectroscopy (NIRS) to measure relative changes in cortical hemodynamics from 19 adult and 19 preschool children (aged 3-4 years old), while they watched epochs of static and motion pictures extracted from TV programs. The spatio-temporal characteristics of oxygenated and deoxygenated hemoglobin volumes (oxy- and deoxy-Hb) of both subject groups were described and compared where appropriate for five regions of interest (ROIs). These were striate, left and right middle temporal, and left and right temporo-parietal areas. Over these areas, deoxy-Hb volumes did not differ between both groups. Preschool data showed significant increases in oxy-Hb over striate, middle temporal and temporo-parietal areas in response to visual motion stimuli. Static stimuli caused a significant oxy-Hb increase over striate and left middle temporal areas. Surprisingly, changes in adult oxy-Hb were not profound and did not show a significant oxy-Hb increase in striate and middle temporal areas in response to the motion stimuli, warranting further research. In spite of oxy-Hb volume differences, oxy-Hb recovery to baseline followed a similar pattern in both groups in response to both static and motion stimuli. Together, the results suggest that near-infrared spectroscopy is a viable method to investigate cortical development of preschool children by monitoring their hemodynamic response patterns. (C) 2011 Elsevier B.V. All rights reserved.
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