4.6 Review

Glioblastoma, Cancer Stem Cells and Hypoxia

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Acriflavine inhibits HIF-1 dimerization, tumor growth, and vascularization

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Daoy medulloblastoma cells that express CD133 are radioresistant relative to CD133- cells, and the CD133+ sector is enlarged by hypoxia

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Hypoxia requires Notch signaling to maintain the undifferentiated cell state

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Low O2 tensions and the prevention of differentiation of hES cells

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MGMT gene silencing and benefit from temozolomide in glioblastoma

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Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

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The oligodendroglial lineage marker OLIG2 is universally expressed in diffuse gliomas

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Socializing with the neighbors: Stem cells and their niche

E Fuchs et al.

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Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line

T Kondo et al.

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Hypoxia is important in the biology and aggression of human glial brain tumors

SM Evans et al.

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SK Singh et al.

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Hypoxia-induced nucleophosmin protects cell death through inhibition of p53

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Cancerous stem cells can arise from pediatric brain tumors

HD Hemmati et al.

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GL Semenza

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Oxygen sensing by primary cardiac fibroblasts -: A key role of p21Waf1/Cip1/Sdi1

S Roy et al.

CIRCULATION RESEARCH (2003)

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Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1α-degradative pathway

JS Isaacs et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)