期刊
BRAIN IMAGING AND BEHAVIOR
卷 3, 期 3, 页码 284-291出版社
SPRINGER
DOI: 10.1007/s11682-009-9070-7
关键词
ERP; MMN; Pattern; Speech; Prosody
类别
资金
- NIMH [NRSA F1-MH067339, K02 MH01439, R01 MH49334, R37 MH49334, NS30029]
- Burroughs Welcome Fund
Modulation of speech conveys information that is decoded within audio-sensory structures. For example, the termination of an utterance with a rise in pitch distinguishes statements and questions. This study evaluated the sensitivity of early auditory structures to such linguistic prosodic distinctions using mismatch negativity (MMN). MMN is a preattentive auditory event-related potential (ERP) sensitive to stimulus deviance. High-density ERP to pitch contour stimuli were collected in a passive listening oddball paradigm from 11 healthy subjects. Voltage analysis revealed significant MMN responses to declarative and interrogative oddball stimuli. Further, MMN was significantly larger to interrogative, than declarative, deviants, indicating non-symmetric brain processing. These MMNs demonstrate that pitch contour abstractions reflecting interrogative/ declarative distinctions can be represented in preattentive auditory sensory memory.
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