期刊
EXPERT REVIEW OF OPHTHALMOLOGY
卷 7, 期 5, 页码 459-470出版社
ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD
DOI: 10.1586/EOP.12.56
关键词
photoreceptor; progenitor cell; scaffold; stem cell; tissue engineering; transplantation
资金
- NIH [EY020297, P30-EY014801]
- Research to Prevent Blindness
- NATIONAL EYE INSTITUTE [RC1EY020297] Funding Source: NIH RePORTER
Retinal degenerations and optic neuropathies often lead to death of photoreceptors or retinal ganglion cells, respectively. Stem cell therapies are showing promise for these diseases in preclinical models and are beginning to transition into human trials, but cell delivery and integration remain major challenges. Focusing on photoreceptor- and progenitor-directed approaches, in this article, the authors review how advances in tissue engineering and cell scaffold design are enhancing cell therapies for retinal degeneration.
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