期刊
INTERNATIONAL JOURNAL OF BEHAVIORAL DEVELOPMENT
卷 36, 期 1, 页码 45-52出版社
SAGE PUBLICATIONS LTD
DOI: 10.1177/0165025411406864
关键词
cognitive control; cortisol; HPA axis; MHPG; monkey; resilience; response inhibition; stress inoculation
资金
- NICHD NIH HHS [R01 HD067175] Funding Source: Medline
- NIDA NIH HHS [R01 DA016902] Funding Source: Medline
- NIMH NIH HHS [R01 MH047573, F32 MH066537, R01 MH077884] Funding Source: Medline
- EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT [R01HD067175] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF MENTAL HEALTH [R01MH047573, R01MH077884, F32MH066537] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE ON DRUG ABUSE [R01DA016902] Funding Source: NIH RePORTER
Monkeys exposed to stress inoculation protocols early in life subsequently exhibit diminished neurobiological responses to moderate psychological stressors and enhanced cognitive control of behavior during juvenile development compared to non-inoculated monkeys. The present experiments extended these findings and revealed that stress inoculated monkeys: (a) mount neurobiological responses equivalent to non-inoculated monkeys when the stressor is of sufficient intensity, and (b) continue to exhibit enhanced cognitive control as young adults compared to non-inoculated monkeys. These results suggest that stress inoculation protocols alter the appraisal of and response to moderate stressors as less threatening and permanently enhance cognitive control, at least through early adulthood. These data therefore support the notion that the stress inoculation phenotype reflects stress resilience rather than stress pathology.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据