3.8 Article

Personalized Diabetes and Cancer Medicine: A Rationale for Anti-Diabetic Nutrition (Bitter Melon) in a Supportive Setting

期刊

CURRENT CANCER THERAPY REVIEWS
卷 8, 期 1, 页码 66-77

出版社

BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/157339412799462521

关键词

Diabetes Type 2; cancer; bitter melon; Momordica charantia L.; human clinical study; prospective and double-blinded; dietary supportive care; personalized medicine

类别

资金

  1. Praevomed GmbH, Gottingen, Germany

向作者/读者索取更多资源

Recent discoveries in epidemiology and molecular epidemiology suggest a link between cancer risk, cancer progression and diabetes risk factors and treatment. Obesity, physical inactivity, smoking, mal nutrition and age are common risk nominators for both diseases. Furthermore due to these risk factors, tumor patients are often comorbid with diabetes type 2. Therefore, it is an urgent need in order to meet at least one risk factor - obesity and mal nutrition - to show that - in a scientifically well-based manner - ethnopharmacology can provide views on plants with health informations. Apart from epidemiological evidence, selected botanicals have to be proven in preclinical and cellular settings, in animal studies for the proof of principle and in clinical trials for their potentials as dietary nutritional care. We have shown here for the first time according to this scientific sequencing of evaluation that a special water soluble Bitter Melon powder is a first candidate to be included into personalized diabetes type 2 and antitumor protocols as dietary supportive care to control the carbohydrate metabolism. The proof of principle to decrease blood glucose values in db/db mice by a Bitter Melon powder was demonstrated and a prospective, randomized, double-blinded and Placebo-controlled trial in diabetes type 2 patients, although continuously throughout the trial under conventional oral therapy, gave evidence for a Bitter Melon powder to be able to decrease HbA1c in a four-months intervention. This study highlights the importance of a significantly evaluated botanical as supportive diet care in tumor and diabetes type 2 patients.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

3.8
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据