期刊
BMC MICROBIOLOGY
卷 14, 期 -, 页码 -出版社
BMC
DOI: 10.1186/s12866-014-0293-4
关键词
Bat Orthoreovirus; Prevalence; Viral genome reassortment
类别
资金
- National Natural Science Foundation of China-Yunnan Province Joint Fund [U1036601]
- National Natural Science Foundation of China [AWS11L009, 81101618]
Background: In recent years novel human respiratory disease agents have been described for Southeast Asia and Australia. The causative pathogens were classified as pteropine orthoreoviruses with a strong phylogenetic relationship to orthoreoviruses of bat origin. Results: In this report, we isolated a novel Melaka-like reovirus (named Cangyuan virus) from intestinal content samples of one fruit bat residing in China's Yunnan province. Phylogenetic analysis of the whole Cangyuan virus genome sequences of segments L, M and S demonstrated the genetic diversity of the Cangyuan virus. In contrast to the L and M segments, the phylogenetic trees for the S segments of Cangyuan virus demonstrated a greater degree of heterogeneity. Conclusions: Phylogenetic analysis indicated that the Cangyuan virus was a novel orthoreovirus and substantially different from currently known members of Pteropine orthoreovirus (PRV) species group.
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