期刊
TISSUE BARRIERS
卷 1, 期 3, 页码 -出版社
TAYLOR & FRANCIS AS
DOI: 10.4161/tisb.24956
关键词
tight junction; peripheral nerve; perineurial cell; perineurium; Schwann cell; endothelial cell; basement membrane; transcytosis
This review introduces the traditionally defined anatomic compartments of the peripheral nerves based on light and electron microscopic topography and then explores the cellular and the most recent molecular basis of the different barrier functions operative in peripheral nerves. We also elucidate where, and how, the homeostasis of the normal human peripheral nerve is controlled in situ and how claudin-containing tight junctions contribute to the barriers of peripheral nerve. Also, the human timeline of the development of the barriers of the peripheral nerve is depicted. Finally, potential future therapeutic modalities interfering with the barriers of the peripheral nerve are discussed.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据