期刊
JOURNAL OF CLINICAL MICROBIOLOGY
卷 53, 期 6, 页码 1968-1975出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.00410-15
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- U.S. Army Medical Research and Materiel Command [W81XWH-13-C-0103]
- Army Research Office of the Department of Defense [W911NF-11-1-0136]
- Office of Congressionally Directed Medical Research Programs
- Joint Warfighter Medical Research Program
- Department of the Navy under the Wounded, Ill, and Injured Program
- military infectious disease research program [D_MIDCTA_I_12_J2_29]
We describe a 22-year-old soldier with 19% total body surface area burns, polytrauma, and sequence- and culture-confirmed Pythium aphanidermatum wound infection. Antemortem histopathology suggested disseminated Pythium infection, including brain involvement; however, postmortem PCR revealed Cunninghamella elegans, Lichtheimia corymbifera, and Saksenaea vasiformis coinfection. The utility of molecular diagnostics in invasive fungal infections is discussed.
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