期刊
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
卷 44, 期 1, 页码 154-167出版社
SPRINGER/PLENUM PUBLISHERS
DOI: 10.1007/s10803-013-1861-4
关键词
Autism spectrum disorder; Broader autism phenotype; High-risk siblings; Receptive language; Expressive language; Language profiles
资金
- Medical Research Council [MR/K021389/1, G0701484] Funding Source: Medline
- MRC [MR/K021389/1, G0701484] Funding Source: UKRI
- Autistica [7221, 7267] Funding Source: researchfish
- National Institute for Health Research [NF-SI-0510-10268] Funding Source: researchfish
Many preschoolers with autism spectrum disorders (ASD) present relative lack of receptive advantage over concurrent expressive language. Such profile emergence was investigated longitudinally in 54 infants at high-risk (HR) for ASD and 50 low-risk controls, with three language measures taken across four visits (around 7, 14, 24, 38 months). HR infants presented three outcome subgroups: ASD, other atypicality, and typical development. Reduced receptive vocabulary advantage was observed in HR infants by 14 months, but was maintained to 24 months only in ASD/other atypicality outcome subgroups while typically-developing HR infants regained a more normative profile. Few group differences appeared on a direct assessment of language and parent-reported functional communication. Processes of early development toward ASD outcome and in intermediate phenotypes are discussed.
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