期刊
TOXICOLOGY REPORTS
卷 1, 期 -, 页码 137-144出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.toxrep.2014.05.009
关键词
Nanotoxicity; Gold nanospheres; Gold nanorods; Silver nanospheres; Silver triangular nanoplates; CdTe/CdS quantum dots; Hela cells; HepG2 cells; SRB
类别
资金
- National Natural Science Foundation of China [61275197, 61205025, 81071886, 81371681]
- Science and Technology Development Project of Jilin Province [20130206105SF]
Optical nanoparticles (NPs) have the potential to provide new tools for diagnosis and treatment of human diseases, however, their nanotoxicity and biological characteristics are still unclear. Here, we prepared a series of typical NPs (including gold nanospheres, gold nanorods, silver nanopheres, silver triangular nanoplates and quantum dots) with different material and surface chemical modification for nanotoxicity test. Cell proliferation was investigated by SRB assay where the NPs were co-cultured with cancer cells. It was found that NPs' toxicity was highly correlated to different factors-material selection, physical size/surface area, shape, and surface chemical property, etc. This work has the potential to provide a uniform and systematic information when they are applied as probes in biological and medical fields. (C) 2014 Published by Elsevier Ireland Ltd. This is an open access article under the CC BY-NC-ND license
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据