期刊
BMC BIOINFORMATICS
卷 19, 期 -, 页码 -出版社
BMC
DOI: 10.1186/s12859-018-2304-1
关键词
Circular RNAs; Divergent primer; Sequence
类别
资金
- National Natural Science Foundation of China [81602551]
- Young Talents Program of Jiangsu Cancer Hospital [2017YQL-10]
- Jiangsu Provincial Women and Children Health Research Project [F201762]
- Jiangsu Province six talent peak personal training project [2016-WSW-086]
Background: Since circular RNAs (circRNAs) post-transcriptionally regulate gene expression, they have attracted increasing attention. However, there is no existing tool to annotate and extract spliced sequences for circRNAs and no tool to determine the specificity of circRNA primers. Results: In this study, we present circPrimer, which allows users to search, annotate, and visualize circRNAs. Additionally, circPrimer enables users to extract the spliced sequences and genomic sequences of any circRNA, including novel circRNAs. Furthermore, circPrimer help users to design primers for circRNAs and to determine the specificity of the circRNA primers. Conclusions: CircPrimer is a user-friendly tool for exploring circRNAs that does not require special user skills.
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