相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。The role of overexpressed DYRK1A protein in the early onset of neurofibrillary degeneration in Down syndrome
Jerzy Wegiel et al.
ACTA NEUROPATHOLOGICA (2008)
Targeted deletion of the calcineurin inhibitor DSCR1 suppresses tumor growth
Sandra Ryeom et al.
CANCER CELL (2008)
被撤回的出版物: c-Jun inhibits thapsigargin-induced ER stress through up-regulation of DSCR1/Adapt78 (Retracted article. See vol. 247, pg. 1609, 2022)
Peng Zhao et al.
EXPERIMENTAL BIOLOGY AND MEDICINE (2008)
Overexpression of Dyrk1A contributes to neurofibrillary degeneration in Down syndrome
Fei Liu et al.
FASEB JOURNAL (2008)
DSCR1/RCAN1 regulates vesicle exocytosis and fusion pore kinetics: implications for Down syndrome and Alzheimer's disease
Damien J. Keating et al.
HUMAN MOLECULAR GENETICS (2008)
Transcription Enhancer Factor 3 (TEF3) Mediates the Expression of Down Syndrome Candidate Region 1 Isoform 1 (DSCR1-1L) in Endothelial Cells
Xin Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Dual-specificity tyrosine(Y)-phosphorylation regulated kinase 1A-mediated phosphorylation of amyloid precursor protein: evidence for a functional link between Down syndrome and Alzheimer's disease
Soo-Ryoon Ryoo et al.
JOURNAL OF NEUROCHEMISTRY (2008)
Increased NR2A expression and prolonged decay of NMDA-induced calcium transient in cerebellum of TgDyrk1A mice, a mouse model of Down syndrome
X. Altafaj et al.
NEUROBIOLOGY OF DISEASE (2008)
THE DOWN SYNDROME CANDIDATE DUAL-SPECIFICITY TYROSINE PHOSPHORYLATION-REGULATED KINASE 1A PHOSPHORYLATES THE NEURODEGENERATION-RELATED SEPTIN 4
J. H. Sitz et al.
NEUROSCIENCE (2008)
NF-κB-inducing kinase phosphorylates and blocks the degradation of down syndrome candidate region 1
Jung Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
The selectivity of protein kinase inhibitors: a further update
Jenny Bain et al.
BIOCHEMICAL JOURNAL (2007)
DYRK1A-mediated hyperphosphorylation of Tau - A functional link between Down syndrome and Alzheimer disease
Soo-Ryoon Ryoo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
The Down syndrome critical region protein RCAN1 regulates long-term potentiation and memory via inhibition of phosphatase signaling
Charles A. Hoeffer et al.
JOURNAL OF NEUROSCIENCE (2007)
Dyrk1A overexpression in immortalized hippocampal cells produces the neuropathological features of Down syndrome
Joongkyu Park et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2007)
Overexpression of DSCR1 blocks zinc-induced neuronal cell death through the formation of nuclear aggregates
Eun Jung Lee et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2007)
RCAN1 (DSCR1) increases neuronal susceptibility to oxidative stress:: a potential pathogenic process in neurodegeneration
Silvia Porta et al.
HUMAN MOLECULAR GENETICS (2007)
Trisomy-driven overexpression of DYRK1A kinase in the brain of subjects with Down syndrome
Wieslaw K. Dowjat et al.
NEUROSCIENCE LETTERS (2007)
Cell cycle alteration and decreased cell proliferation in the hippocampal dentate gyrus and in the neocortical germinal matrix of fetuses with down syndrome and in Ts65Dn mice
Andrea Contestabile et al.
HIPPOCAMPUS (2007)
Down syndrome candidate region 1 increases the stability of the IκBα protein -: Implications for its anti-inflammatory effects
Young Sun Kim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Phosphorylation inhibits turnover of the tau protein by the proteasome:: influence of RCAN1 and oxidative stress
Diana Poppek et al.
BIOCHEMICAL JOURNAL (2006)
Dyrk1A phosphorylates α-synuclein and enhances intracellular inclusion formation
Eun Joo Kim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Down syndrome candidate region 1 isoform 1 mediates angiogenesis through the calcineurin-NFAT pathway
Liuliang Qin et al.
MOLECULAR CANCER RESEARCH (2006)
Functional characterization of the calcipressin motif that suppresses calcineurin-mediated NFAT-dependent cytokine gene expression in human T cells
Anna Aubareda et al.
CELLULAR SIGNALLING (2006)
Phosphorylation of amphiphysin I by minibrain kinase/dual-specificity tyrosine phosphorylation-regulated kinase, a kinase implicated in Down syndrome
Noriko Murakami et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Hippocampal hypocellularity in the Ts65Dn mouse originates early in development
Hernan A. Lorenzi et al.
BRAIN RESEARCH (2006)
Thrombin-induced autoinhibitory factor, Down syndrome critical region-1, attenuates NFAT-dependent vascular cell adhesion molecule-1 expression and inflammation in the endothelium
Takashi Minami et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
DYRKIA BAC transgenic mice show altered synaptic plasticity with learning and memory defects
Kyoung-Jin Ahn et al.
NEUROBIOLOGY OF DISEASE (2006)
NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21
Joseph R. Arron et al.
NATURE (2006)
A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT
Yousang Gwack et al.
NATURE (2006)
Protein kinase-mediated regulation of calcineurin through the phosphorylation of modulatory calcineurin-interacting protein 1
S Abbasi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
DSCR1 (ADAPT78) lethality:: Evidence for a protective effect of trisomy 21 genes?
KS Kluetzman et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
The essential role of MEKK3 signaling in angiotensin II-induced calcineurin/nuclear factor of activated T-cells activation
S Abbasi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Constitutive Dyrk1A is abnormally expressed in Alzheimer disease, Down syndrome, Pick disease, and related transgenic models
I Ferrer et al.
NEUROBIOLOGY OF DISEASE (2005)
Drosophila melanogaster homolog of Down syndrome critical region 1 is critical for mitochondrial function
KT Chang et al.
NATURE NEUROSCIENCE (2005)
An aneuploid mouse strain carrying human chromosome 21 with Down syndrome phenotypes
A O'Doherty et al.
SCIENCE (2005)
Proliferation dynamics in cultured skin fibroblasts from Down syndrome subjects
M Kimura et al.
FREE RADICAL BIOLOGY AND MEDICINE (2005)
Regulation of the proapoptotic activity of huntingtin interacting protein 1 by Dyrk1 and caspase-3 in hippocampal neuroprogenitor cells
JE Kang et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2005)
Aggregate formation and synaptic abnormality induced by DSCR1
H Ma et al.
JOURNAL OF NEUROCHEMISTRY (2004)
Phosphorylation of Ser640 in muscle glycogen synthase by DYRK family protein kinases
AV Skurat et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Chromosome 21 and Down syndrome: From genomics to pathophysiology
SE Antonarakis et al.
NATURE REVIEWS GENETICS (2004)
VEGF selectively induces Down syndrome critical region I gene expression in endothelial cells: a mechanism for feedback regulation of angiogenesis?
YG Yao et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Down syndrome candidate region 1, a downstream target of VEGF, participates in endothelial cell migration and angiogenesis
M Iizuka et al.
JOURNAL OF VASCULAR RESEARCH (2004)
Down syndrome critical region protein 1 (DSCR1), a novel VEGF target gene that regulates expression of inflammatory markers on activated endothelial cells
BA Hesser et al.
BLOOD (2004)
GSK-3 kinases enhance calcineurin signaling by phosphorylation of RCNs
Z Hilioti et al.
GENES & DEVELOPMENT (2004)
Vascular endothelial growth factor-and thrombin-induced termination factor, down syndrome critical region-1, attenuates endothelial cell proliferation and angiogenesis
T Minami et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Identification of novel direct transcriptional targets of glucocorticoid receptor
M U et al.
LEUKEMIA (2004)
Deficits of neuronal density in CA1 and synaptic density in the dentate gyrus, CA3 and CA1, in a mouse model of Down syndrome
MA Kurt et al.
BRAIN RESEARCH (2004)
The Drosophila homolog of Down's syndrome critical region 1 gene regulates learning:: Implications for mental retardation
KT Chang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Oxidative and calcium stress regulate DSCR1 (Adapt78/MCIP1) protein
HY Lin et al.
FREE RADICAL BIOLOGY AND MEDICINE (2003)
Phosphorylation of calcipressin 1 increases its ability to inhibit calcineurin and decreases calcipressin half-life
L Genescà et al.
BIOCHEMICAL JOURNAL (2003)
The specificities of protein kinase inhibitors: an update
J Bain et al.
BIOCHEMICAL JOURNAL (2003)
Dual roles of modulatory calcineurin-interacting protein 1 in cardiac hypertrophy
RB Vega et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
The brain in Down syndrome (TRISOMY 21)
G Lubec et al.
JOURNAL OF NEUROLOGY (2002)
Multiple domains of MCIP1 contribute to inhibition of calcineurin activity
RB Vega et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The DSCR1 (Adapt78) isoform 1 protein calcipressin 1 inhibits calcineurin and protects against acute calcium-mediated stress damage, including transient oxidative stress
G Ermak et al.
FASEB JOURNAL (2002)
Dynamin is a minibrain kinase/dual specificity Yak1-related kinase 1A substrate
MC Chen-Hwang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Protein kinase Dyrk1 activates cAMP response element-binding protein during neuronal differentiation in hippocampal progenitor cells
EJ Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Chronic overexpression of the calcineurin inhibitory gene DSCR1 (Adapt78) is associated with Alzheimer's disease
G Ermak et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down's syndrome
X Altafaj et al.
HUMAN MOLECULAR GENETICS (2001)
Myocyte-enriched calcineurin-interacting protein, MCIP1, inhibits cardiac hypertrophy in vivo
BA Rothermel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Molecular genetics: Unmasking polyglutamine triggers in neurodegenerative disease
JF Gusella et al.
NATURE REVIEWS NEUROSCIENCE (2000)
adapt78 protects cells against stress damage and suppresses cell growth
KP Leahy et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2000)
DSCR1, overexpressed in Down syndrome, is an inhibitor of calcineurin-mediated signaling pathways
JJ Fuentes et al.
HUMAN MOLECULAR GENETICS (2000)
A protein encoded within the Down syndrome critical region is enriched in striated muscles and inhibits calcineurin signaling
B Rothermel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Specificity determinants of substrate recognition by the protein kinase DYRK1A
S Himpel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Risks of leukaemia and solid tumours in individuals with Down's syndrome
H Hasle et al.
LANCET (2000)
分享论文
