期刊
BLOOD PURIFICATION
卷 38, 期 3-4, 页码 244-252出版社
KARGER
DOI: 10.1159/000366124
关键词
Haemodialysis; Magnesium; Mortality; Vascular calcifications
Background: Hypomagnesaemia is a cardiovascular (CV) risk factor in the general population. The aim of this study was to evaluate the relationship between pre-dialysis magnesium (Mg) and CV risk markers, [including pulse pressure (PP), left ventricular mass index (LVMI) and vascular calcifications (VC)], and mortality in haemodialysis (HD) patients. Methods: We performed a 48-month prospective study in 206 patients under pre-dilution haemodiafiltration with a dialysate Mg concentration of 1 mmol/l. Results: Lower Mg concentrations were predictors of an increased PP (>= 65 mm Hg) (p = 0.002) and LVMI (>= 140 g/m(2)) (p = 0.03) and of a higher VC score (>= 3) (p = 0.01). Patients with Mg < 1.15 mmol/l had a lower survival at the end of the study (p = 0.01). Serum Mg < 1.15 mmol/l was an independent predictor of all-cause (p = 0.01) and CV mortality (p = 0.02) when adjusted for multiple CV risk factors. Conclusions: Lower Mg levels seem to be associated with increased CV risk markers, like PP, LVMI and VC, and with higher mortality in HD patients. (C) 2015 S. Karger AG, Basel
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据