期刊
PROGRESS ON CHEMISTRY AND APPLICATION OF CHITIN AND ITS DERIVATIVES
卷 20, 期 -, 页码 170-176出版社
POLISH CHITIN SOC
DOI: 10.15259/PCACD.20.16
关键词
chitosan; hyaluronic acid; polymer blends; viscosity interaction parameters; AFM microscopy
资金
- National Science Centre (NCN, Poland) [UMO-2013/11/B/ST8/04444]
In the present study, the results of viscosity measurements in dilute solutions of chitosan (Ch) with hyaluronic acid (HA) are presented. Chitosan is blended with hyaluronic acid in aqueous 0.1M CH3COOH/0.2M NaCl and 0.3M NaCl respectively, or with the addition of HEPES. Viscosity measurements of dilute polymer solution were carried out in an Ubbelohde capillary viscometer. The intrinsic viscosity, [eta], and the viscosity interaction parameters, b(m), have been determined for the binary (solvent/polymer) and ternary (solvent/polymer A/polymer B) systems. The homogeneity and morphology of chitosan blends were ascertained from the tapping-mode atomic force microscopy. The surface roughness of chitosan, hyaluronic acid and Ch/HA blended films was altered by mixing. The obtained results suggested that there was existence of the strong interactions between chitosan and hyaluronic acid.
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