相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Testosterone administration inhibits hepcidin transcription and is associated with increased iron incorporation into red blood cells
Wen Guo et al.
AGING CELL (2013)
Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME
Patricio Godoy et al.
ARCHIVES OF TOXICOLOGY (2013)
Hepcidin levels in diabetes mellitus and polycystic ovary syndrome
A. H. Sam et al.
DIABETIC MEDICINE (2013)
mTOR Signaling in Growth Control and Disease
Mathieu Laplante et al.
CELL (2012)
An integrative model links multiple inputs and signaling pathways to the onset of DNA synthesis in hepatocytes
Jeremy Huard et al.
FEBS JOURNAL (2012)
Inhibition of hepcidin transcription by growth factors
Julia B. Goodnough et al.
HEPATOLOGY (2012)
RASA1 maintains the lymphatic vasculature in a quiescent functional state in mice
Philip E. Lapinski et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Increased Serum Hepcidin Levels in Subjects with the Metabolic Syndrome: A Population Study
Nicola Martinelli et al.
PLOS ONE (2012)
Identification of a common variant in the TFR2 gene implicated in the physiological regulation of serum iron levels
Irene Pichler et al.
HUMAN MOLECULAR GENETICS (2011)
IL-6 Increases MMP-13 Expression and Motility in Human Chondrosarcoma Cells
Chih-Hsin Tang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
S6 kinase 1 is required for rapamycin-sensitive liver proliferation after mouse hepatectomy
Catherine Espeillac et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Downregulation of hemojuvelin prevents inhibitory effects of bone morphogenetic proteins on iron metabolism in hepatocellular carcinoma
Ulrike Maegdefrau et al.
LABORATORY INVESTIGATION (2011)
The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored
Damian Szklarczyk et al.
NUCLEIC ACIDS RESEARCH (2011)
SMAD7 controls iron metabolism as a potent inhibitor of hepcidin expression
Katarzyna Mleczko-Sanecka et al.
BLOOD (2010)
Two to Tango: Regulation of Mammalian Iron Metabolism
Matthias W. Hentze et al.
CELL (2010)
Molecular basis of iron-loading disorders
Deepak Darshan et al.
EXPERT REVIEWS IN MOLECULAR MEDICINE (2010)
Defective Bone Morphogenic Protein Signaling Underlies Hepcidin Deficiency in HFE Hereditary Hemochromatosis
John D. Ryan et al.
HEPATOLOGY (2010)
Factors influencing disease phenotype and penetrance in HFE haemochromatosis
J. Rochette et al.
HUMAN GENETICS (2010)
Anaemia, microcytosis and sirolimus-is iron the missing link?
Sofia Sofroniadou et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2010)
The role of iron in type 2 diabetes in humans
Swapnil N. Rajpathak et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2009)
BMP/Smad signaling is not enhanced in Hfe-deficient mice despite increased Bmp6 expression
Leon Kautz et al.
BLOOD (2009)
Identification of TWSG1 as a second novel erythroid regulator of hepcidin expression in murine and human cells
Toshihiko Tanno et al.
BLOOD (2009)
Bone Morphogenetic Protein Signaling Is Impaired in an Hfe Knockout Mouse Model of Hemochromatosis
Elena Corradini et al.
GASTROENTEROLOGY (2009)
Cross-talk between the mitogen activated protein kinase and bone morphogenetic protein/hemojuvelin pathways is required for the induction of hepcidin by holotransferrin in primary mouse hepatocytes
Guillemette Ramey et al.
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL (2009)
Combined Deletion of Hfe and Transferrin Receptor 2 in Mice Leads to Marked Dysregulation of Hepcidin and Iron Overload
Daniel F. Wallace et al.
HEPATOLOGY (2009)
Bone morphogenetic protein (BMP)-responsive elements located in the proximal and distal hepcidin promoter are critical for its response to HJV/BMP/SMAD
Guillem Casanovas et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2009)
Lack of the bone morphogenetic protein BMP6 induces massive iron overload
Delphine Meynard et al.
NATURE GENETICS (2009)
BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism
Billy Andriopoulos et al.
NATURE GENETICS (2009)
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
Da Wei Huang et al.
NATURE PROTOCOLS (2009)
Erythropoietin mediates hepcidin expression in hepatocytes through EPOR signaling and regulation of C/EBPα
Jorge P. Pinto et al.
BLOOD (2008)
Hfe acts in hepatocytes to prevent hemochromatosis
Maja Vujic Spasic et al.
CELL METABOLISM (2008)
The Serine Protease Matriptase-2 (TMPRSS6) Inhibits Hepcidin Activation by Cleaving Membrane Hemojuvelin
Laura Silvestri et al.
CELL METABOLISM (2008)
Molecular Mechanisms of Hepatocellular Carcinoma
Rajagopal N. Aravalli et al.
HEPATOLOGY (2008)
Hepatitis C Virus-induced Oxidative Stress Suppresses Hepcidin Expression Through Increased Histone Deacetylase Activity
Kouichi Miura et al.
HEPATOLOGY (2008)
A bone morphogenetic protein (BMP)-responsive element in the hepcidin promoter controls HFE2-mediated hepatic hepcidin expression and its response to IL-6 in cultured cells
Maria Vittoria Verga Falzacappa et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2008)
Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA)
Karin E. Finberg et al.
NATURE GENETICS (2008)
Sorafenib in advanced hepatocellular carcinoma
Josep M. Llovet et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
The serine protease TMPRSS6 is required to sense iron deficiency
Xin Du et al.
SCIENCE (2008)
Generation of mice with a conditional allele of the p120 Ras GTPase-activating protein
Philip E. Lapinski et al.
GENESIS (2007)
High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin
Toshihiko Tanno et al.
NATURE MEDICINE (2007)
Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs)
Carole Peyssonnaux et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Systems genetic analysis of peripheral iron parameters in the mouse
Byron C. Jones et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2007)
Downregulation of death-associated protein kinase 1 (DAPK1) in chronic lymphocytic leukemia
Aparna Raval et al.
CELL (2007)
GEFs and GAPs: Critical elements in the control of small G proteins
Johannes L. Bos et al.
CELL (2007)
Infrared-based protein detection arrays for quantitative proteomics
Christian Loebke et al.
PROTEOMICS (2007)
Integration of biological networks and gene expression data using Cytoscape
Melissa S. Cline et al.
NATURE PROTOCOLS (2007)
STAT3 mediates hepatic hepcidin expression and its inflammatory stimulation
Maria Vittoria Verga Falzacappa et al.
BLOOD (2007)
Interleukin induces hepcidin expression through STAT3
Diedra M. Wrighting et al.
BLOOD (2006)
Multiple polymorphic loci determine basal hepatic and splenic iron status in mice
Gemma R. Grant et al.
HEPATOLOGY (2006)
Transcription factor YY1: structure, function, and therapeutic implications in cancer biology
S Gordon et al.
ONCOGENE (2006)
Analysis of cell-based RNAi screens
Michael Boutros et al.
GENOME BIOLOGY (2006)
A role of SMAD4 in iron metabolism through the positive regulation of hepicidin expression
RH Wang et al.
CELL METABOLISM (2005)
RASA1: variable phenotype with capillary and arteriovenous malformations
LM Boon et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2005)
A combined syndrome of juvenile polyposis and hereditary haemorrhagic telanglectasia associated with mutations in MADH4 (SMAD4)
CJ Gallione et al.
LANCET (2004)
Signal transduction of bone morphogenetic protein receptors
A Nohe et al.
CELLULAR SIGNALLING (2004)
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
E Nemeth et al.
SCIENCE (2004)
Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis
G Papanikolaou et al.
NATURE GENETICS (2004)
Liver regeneration: From myth to mechanism
R Taub
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)
Multigenic control of hepatic iron loading in a murine model of hemochromatosis
M Bensaid et al.
GASTROENTEROLOGY (2004)
SMAD-mediated modulation of YY1 activity regulates the BMP response and cardiac-specific expression of a GATA4/5/6dependent chick Nkx2.5 enhancer
KH Lee et al.
DEVELOPMENT (2004)
IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin
E Nemeth et al.
JOURNAL OF CLINICAL INVESTIGATION (2004)
Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis
KR Bridle et al.
LANCET (2003)
Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis
A Roetto et al.
NATURE GENETICS (2003)
Nrdpl/FLRF is a ubiquitin ligase promoting ubiquitination and degradation of the epidermal growth factor receptor family member, ErbB3
XB Qiu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Novel protein kinase C isoforms regulate human keratinocyte differentiation by activating a p38δ mitogen-activated protein kinase cascade that targets CCAAT/enhancer-binding protein α
T Eftmova et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Mouse strain differences determine severity of iron accumulation in Hfe knockout model of hereditary hemochromatosis
RE Fleming et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
A novel mammalian iron-regulated protein involved in intracellular iron metabolism
S Abboud et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
分享论文
