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Soheil Meshinchi et al.
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Susanne Reymann et al.
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Hans C. Zaun et al.
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LE Gerweck et al.
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CH Brandts et al.
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LK Putney et al.
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AA Borisy et al.
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J Mailänder et al.
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HJ Park et al.
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S Matsuyama et al.
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