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Coagulation factor VA2440G causes east Texas bleeding disorder via TFPIα
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Direct inhibition of factor VIIa by TFPI and TFPI constructs
S. Peraramelli et al.
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Comparison of the inhibitory activities of human tissue factor pathway inhibitor (TFPI)α and TFPIβ
S. A. Maroney et al.
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Aptamer BAX499 mediates inhibition of tissue factor pathway inhibitor via interaction with multiple domains of the protein
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Tissue factor pathway inhibitor-alpha inhibits prothrombinase during the initiation of blood coagulation
Jeremy P. Wood et al.
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Caveolae optimize tissue factor-Factor VIIa inhibitory activity of cell-surface-associated tissue factor pathway inhibitor
Susan A. Maroney et al.
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TFPIβ is the GPI-anchored TFPI isoform on human endothelial cells and placental microsomes
Thomas J. Girard et al.
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Identification of functionally important residues in TFPI Kunitz domain 3 required for the enhancement of its activity by protein S
Josefin Ahnstroem et al.
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Hemostatic effect of a monoclonal antibody mAb 2021 blocking the interaction between FXa and TFPI in a rabbit hemophilia model
Ida Hilden et al.
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Tissue factor pathway inhibitor: structure-function
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A Bipartite Autoinhibitory Region within the B-domain Suppresses Function in Factor V
Mettine H. A. Bos et al.
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The C-terminus of tissue factor pathway inhibitor a is required for its interaction with factors V and Va
M. Ndonwi et al.
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Inhibition of tissue factor pathway inhibitor by the aptamer BAX499 improves clotting of hemophilic blood and plasma
M. E. Gorczyca et al.
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Absence of hematopoietic tissue factor pathway inhibitor mitigates bleeding in mice with hemophilia
Susan A. Maroney et al.
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The Kunitz 1 and Kunitz 3 domains of tissue factor pathway inhibitor are required for efficient inhibition of factor Xa
Sameera Peraramelli et al.
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Effect of BAX499 aptamer on tissue factor pathway inhibitor function and thrombin generation in models of hemophilia
Matthew Gissel et al.
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Murine Hematopoietic Cell Tissue Factor Pathway Inhibitor Limits Thrombus Growth
Susan A. Maroney et al.
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Extracellular histones promote thrombin generation through platelet-dependent mechanisms: involvement of platelet TLR2 and TLR4
Fabrizio Semeraro et al.
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Activated protein C up-regulates procoagulant tissue factor activity on endothelial cells by shedding the TFPI Kunitz 1 domain
Reto A. Schuepbach et al.
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Aptamer ARC19499 mediates a procoagulant hemostatic effect by inhibiting tissue factor pathway inhibitor
Emily K. Waters et al.
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Downregulation of TFPI in breast cancer cells induces tyrosine phosphorylation signaling and increases metastatic growth by stimulating cell motility
Benedicte Stavik et al.
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Residual platelet factor V ensures thrombin generation in patients with severe congenital factor V deficiency and mild bleeding symptoms
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Endothelial-derived tissue factor pathway inhibitor regulates arterial thrombosis but is not required for development or hemostasis
Thomas A. White et al.
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The Kunitz-3 domain of TFPI-α is required for protein S-dependent enhancement of factor Xa inhibition
Matthew Ndonwi et al.
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Similar hypercoagulable state and thrombosis risk in type I and type III protein S-deficient individuals from families with mixed type I/III protein S deficiency
Elisabetta Castoldi et al.
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Thrombin generation-based assays to measure the activity of the TFPI-protein S pathway in plasma from normal and protein S-deficient individuals
L. F. A. Maurissen et al.
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Hereditary and acquired protein S deficiencies are associated with low TFPI levels in plasma
E. Castoldi et al.
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Alternatively spliced isoforms of tissue factor pathway inhibitor
Susan A. Maroney et al.
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Temporal expression of alternatively spliced forms of tissue factor pathway inhibitor in mice
S. A. Maroney et al.
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Efficacy and safety of a new-class hemostatic drug candidate, AV513, in dogs with hemophilia A
Srinivasa Prasad et al.
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Low plasma levels of tissue factor pathway inhibitor in patients with congenital factor V deficiency
Connie Duckers et al.
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Tissue factor pathway inhibitor-γ is an active alternatively spliced form of tissue factor pathway inhibitor present in mice but not in humans
S. A. Maroney et al.
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Protein S enhances the tissue factor pathway inhibitor inhibition of factor Xa but not its inhibition of factor VIIa-tissue factor
M. Ndonwi et al.
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Inhibitory sequences within the B-domain stabilize circulating factor V in an inactive state
Hua Zhu et al.
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Active tissue factor pathway inhibitor is expressed on the surface of coated platelets
Susan A. Maroney et al.
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Disposition of tissue factor pathway inhibitor during cardiopulmonary bypass
BS Donahue et al.
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Protein S stimulates inhibition of the tissue factor pathway by tissue factor pathway inhibitor
TM Hackeng et al.
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Polyphosphate modulates blood coagulation and fibrinolysis
SA Smith et al.
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Species-specific variation of alternative splicing and transcriptional initiation in six eukaryotes
H Nagasaki et al.
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Comparison of cell-surface TFPIα and β
O Piro et al.
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Caveolin-1 enhances tissue factor pathway inhibitor exposure and function on the cell surface
C Lupu et al.
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Regulation of tissue factor-induced signaling by endogenous and recombinant tissue factor pathway inhibitor
J Ahamed et al.
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Polyphosphate content and fine structure of acidocalcisomes of Plasmodium faiciparum
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Glycosyl phosphatidylinositol anchorage of tissue factor pathway inhibitor
J Zhang et al.
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Low levels of tissue factor pathway inhibitor (TFPI) increase the risk of venous thrombosis
A Dahm et al.
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Characterization of the association of tissue factor pathway inhibitor with human placenta
AE Mast et al.
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Structural and functional characterization of tissue factor pathway inhibitor following degradation by matrix metalloproteinase-8
AC Cunningham et al.
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Lethal perinatal thrombosis in mice resulting from the interaction of tissue factor pathway inhibitor deficiency and Factor V Leiden
DT Eitzman et al.
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Contribution of regions distal to glycine-160 to the anticoagulant activity of tissue factor pathway inhibitor
JM Lockett et al.
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Mechanistic coupling of protease signaling and initiation of coagulation by tissue factor
M Riewald et al.
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Deficiency of tissue factor pathway inhibitor promotes atherosclerosis and thrombosis in mice
RJ Westrick et al.
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Regulation of monocyte procoagulant activity in acute myocardial infarction:: role of tissue factor and tissue factor pathway inhibitor-1
I Ott et al.
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Characterization of a novel autosomal dominant bleeding disorder in a large kindred from east Texas
SQ Kuang et al.
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Fluid flow induces upregulation of synthesis and release of tissue factor pathway inhibitor in vitro
AD Westmuckett et al.
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Detergent-insoluble GPI-anchored proteins are apically sorted in Fischer rat thyroid cells, but interference with cholesterol or sphingolipids differentially affects detergent insolubility and apical sorting
C Lipardi et al.
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Reversible regulation of tissue factor-induced coagulation by glycosyl phosphatidylinositol-anchored tissue factor pathway inhibitor
I Ott et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2000)
Altered plasma antigen levels of tissue factor pathway inhibitor during open-heart surgery
LB Sun et al.
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