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注意：仅列出部分参考文献，下载原文获取全部文献信息。Additional genetic abnormalities significantly worsen poor prognosis associated with 1q21 amplification in multiple myeloma patients
Norbert Grzasko et al.
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Progression in Smoldering Myeloma Is Independently Determined by the Chromosomal Abnormalities del(17p), t(4;14), Gain 1q, Hyperdiploidy, and Tumor Load
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Minor clone provides a reservoir for relapse in multiple myeloma
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Intraclonal heterogeneity and distinct molecular mechanisms characterize the development of t(4;14) and t(11;14) myeloma
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BLOOD (2012)
Whole-genome sequencing of multiple myeloma from diagnosis to plasma cell leukemia reveals genomic initiating events, evolution, and clonal tides
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Clonal competition with alternating dominance in multiple myeloma
Jonathan J. Keats et al.
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Identification of unbalanced genome copy number abnormalities in patients with multiple myeloma by single-nucleotide polymorphism genotyping microarray analysis
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INTERNATIONAL JOURNAL OF HEMATOLOGY (2012)
Long-Term Analysis of the IFM 99 Trials for Myeloma: Cytogenetic Abnormalities [t(4;14), del(17p), 1q gains] Play a Major Role in Defining Long-Term Survival
Herve Avet-Loiseau et al.
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A novel prognostic model in myeloma based on co-segregating adverse FISH lesions and the ISS: analysis of patients treated in the MRC Myeloma IX trial
K. D. Boyd et al.
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SNP-based mapping arrays reveal high genomic complexity in monoclonal gammopathies, from MGUS to myeloma status
L. Lopez-Corral et al.
LEUKEMIA (2012)
A gene expression signature for high-risk multiple myeloma
R. Kuiper et al.
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The genetic architecture of multiple myeloma
Gareth J. Morgan et al.
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Chromosomal Aberrations+1q21 and del(17p13) Predict Survival in Patients With Recurrent Multiple Myeloma Treated With Lenalidomide and Dexamethasone
Ulrike Klein et al.
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The Progression from MGUS to Smoldering Myeloma and Eventually to Multiple Myeloma Involves a Clonal Expansion of Genetically Abnormal Plasma Cells
Lucia Lopez-Corral et al.
CLINICAL CANCER RESEARCH (2011)
Clinical and biological implications of MYC activation: a common difference between MGUS and newly diagnosed multiple myeloma
W-J Chng et al.
LEUKEMIA (2011)
Impact of cytogenetics in patients with relapsed or refractory multiple myeloma treated with bortezomib: Adverse effect of 1q21 gains
Hong Chang et al.
LEUKEMIA RESEARCH (2011)
A compendium of myeloma-associated chromosomal copy number abnormalities and their prognostic value
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1q12 chromosome translocations form aberrant heterochromatic foci associated with changes in nuclear architecture and gene expression in B cell lymphoma
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EMBO MOLECULAR MEDICINE (2010)
Recurrent involvement of heterochromatic regions in multiple myeloma-A multicolor FISH study
Kathrin Lange et al.
LEUKEMIA RESEARCH (2010)
The landscape of somatic copy-number alteration across human cancers
Rameen Beroukhim et al.
NATURE (2010)
Evidence for a novel mechanism for gene amplification in multiple myeloma: 1q12 pericentromeric heterochromatin mediates breakage-fusion-bridge cycles of a 1q12∼23 amplicon
Jeffrey R. Sawyer et al.
BRITISH JOURNAL OF HAEMATOLOGY (2009)
Prognostic Significance of Copy-Number Alterations in Multiple Myeloma
Herve Avet-Loiseau et al.
JOURNAL OF CLINICAL ONCOLOGY (2009)
Gene mapping and expression analysis of 16q loss of heterozygosity identifies WWOX and CYLD as being important in determining clinical outcome in multiple myeloma
Matthew W. Jenner et al.
BLOOD (2007)
A validated gene expression model of high-risk multiple myeloma is defined by deregulated expression of genes mapping to chromosome 1
John D. Shaughnessy et al.
BLOOD (2007)
Genetics and epigenetics of 1q rearrangements in hematological malignancies
A. Fournier et al.
CYTOGENETIC AND GENOME RESEARCH (2007)
The molecular classification of multiple myeloma
Fenghuang Zhan et al.
BLOOD (2006)
Frequent gain of chromosome band 1q21 in plasma-cell dyscrasias detected by fluorescence in situ hybridization: incidence increases from MGUS to relapsed myeloma and is related to prognosis and disease progression following tandem stem-cell transplantation
Ichiro Hanamura et al.
BLOOD (2006)
Integration of global SNP-based mapping and expression arrays reveals key regions, mechanisms, and genes important in the pathogenesis of multiple myeloma
Brian A. Walker et al.
BLOOD (2006)
High-resolution genomic profiles define distinct clinico-pathogenetic subgroups of multiple myeloma patients
DR Carrasco et al.
CANCER CELL (2006)
Genomic instability in multiple myeloma: Evidence for jumping segmental duplications of chromosome arm Iq
JR Sawyer et al.
GENES CHROMOSOMES & CANCER (2005)
Myeloid cell factor-1 is a critical survival factor for multiple myeloma
B Zhang et al.
BLOOD (2002)
Multiple myeloma: Evolving genetic events and host interactions
WM Kuehl et al.
NATURE REVIEWS CANCER (2002)
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