相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Knock-in of a FLT3/ITD mutation cooperates with a NUP98-HOXD13 fusion to generate acute myeloid leukemia in a mouse model
Sarah Greenblatt et al.
BLOOD (2012)
FLT3 ligand impedes the efficacy of FLT3 inhibitors in vitro and in vivo
Takashi Sato et al.
BLOOD (2011)
FLT3 Inhibitors in the Treatment of Acute Myeloid Leukemia The Start of an Era?
Naveen Pemmaraju et al.
CANCER (2011)
Effect of Simvastatin on Cetuximab Resistance in Human Colorectal Cancer With KRAS Mutations
Jeeyun Lee et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2011)
Further activation of FLT3 mutants by FLT3 ligand
R. Zheng et al.
ONCOGENE (2011)
Differential signaling of Flt3 activating mutations in acute myeloid leukemia: a working model
Perry M. Chan
PROTEIN & CELL (2011)
Exploiting the mevalonate pathway to distinguish statin-sensitive multiple myeloma
James W. Clendening et al.
BLOOD (2010)
Lovastatin induces apoptosis of ovarian cancer cells and synergizes with doxorubicin: potential therapeutic relevance
Anna Martirosyan et al.
BMC CANCER (2010)
A novel molecular mechanism of primary resistance to FLT3-kinase inhibitors in AML
Frank Breitenbuecher et al.
BLOOD (2009)
Activation of ER stress and inhibition of EGFR N-glycosylation by tunicamycin enhances susceptibility of human non-small cell lung cancer cells to erlotinib
Yi-He Ling et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2009)
Mislocalized Activation of Oncogenic RTKs Switches Downstream Signaling Outcomes
Chunaram Choudhary et al.
MOLECULAR CELL (2009)
Knock-in of an internal tandem duplication mutation into murine FLT3 confers myeloproliferative disease in a mouse model
Li Li et al.
BLOOD (2008)
FLT3 inhibitors in acute myeloid leukemia
Khaled el-Shami et al.
EXPERT REVIEW OF HEMATOLOGY (2008)
MLL-AF9 and FLT3 cooperation in acute myelogenous leukemia: development of a model for rapid therapeutic assessment
M. C. Stubbs et al.
LEUKEMIA (2008)
FLT3 mutations confer enhanced proliferation and survival properties to multipotent progenitors in a murine model of chronic myelomonocytic leukemia
Benjamin H. Lee et al.
CANCER CELL (2007)
Lovastatin suppresses erythropoietin receptor surface expression through dual inhibition of glycosylation and geranylgeranylation
Sumaya N. Hamadmad et al.
BIOCHEMICAL PHARMACOLOGY (2007)
Prolonged exposure to FLT3 inhibitors leads to resistance via activation of parallel signaling pathways
Obdulio Piloto et al.
BLOOD (2007)
FLT3 inhibition in acute myeloid leukaemia
Steven Knapper
BRITISH JOURNAL OF HAEMATOLOGY (2007)
Pharmacodynamic effects of high dose lovastatin in subjects with advanced malignancies
SA Holstein et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2006)
Clinical resistance to the kinase inhibitor PKC412 in acute myeloid leukemia by mutation of Asn-676 in the FLT3 tyrosine kinase domain
F Heidel et al.
BLOOD (2006)
FLT3-ITD and tyrosine kinase domain mutants induce 2 distinct phenotypes in a murine bone marrow transplantation model
R Grundler et al.
BLOOD (2005)
Pim-1 is up-regulated by constitutively activated FLT3 and plays a role in FLT3-mediated cell survival
KT Kim et al.
BLOOD (2005)
Prediction of resistance to small molecule FLT3 inhibitors: Implications for molecularly targeted therapy of acute leukemia
J Cools et al.
CANCER RESEARCH (2004)
Abrogation of insulin-like growth factor-I (IGF-I) and insulin action by mevalonic acid depletion - Synergy between protein prenylation and receptor glycosylation pathways
KW Siddals et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Variable sensitivity of FLT3 activation loop mutations to the small molecule tyrosine kinase inhibitor MLN518
JJ Clark et al.
BLOOD (2004)
Mevastatin can increase toxicity in primary AMLs exposed to standard therapeutic agents, but statin efficacy is not simply associated with ras hotspot mutations or overexpression
DL Stirewalt et al.
LEUKEMIA RESEARCH (2003)
FLT3 and its role in the pathogenesis of acute myeloid leukaemia
JT Reilly
LEUKEMIA & LYMPHOMA (2003)
Inhibition of the transforming activity of FLT3 internal tandem duplication mutants from AML patients by a tyrosine kinase inhibitor
KF Tse et al.
LEUKEMIA (2002)
FLT3 internal tandem duplication mutations associated with human acute myeloid leukemias induce myeloproliferative disease in a murine bone marrow transplant model
LM Kelly et al.
BLOOD (2002)
Identification of novel FLT-3 Asp835 mutations in adult acute myeloid leukaemia
FM Abu-Duhier et al.
BRITISH JOURNAL OF HAEMATOLOGY (2001)
Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies
Y Yamamoto et al.
BLOOD (2001)
Flt3 ligand induces tyrosine phosphorylation of Gab1 and Gab2 and their association with Shp-2, grb2, and P13 kinase
SL Zhang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)
Constitutive activation of FLT3 stimulates multiple intracellular signal transducers and results in transformation
KF Tse et al.
LEUKEMIA (2000)
分享论文
