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K-RasG12D-induced T-cell lymphoblastic lymphoma/leukemias harbor Notch1 mutations and are sensitive to γ-secretase inhibitors
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FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to γ-secretase inhibitors
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JOURNAL OF EXPERIMENTAL MEDICINE (2007)
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Tumor growth need not be driven by rare cancer stem cells
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Notch-dependent T-lineage commitment occurs at extrathymic sites following bone marrow transplantation
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Notch1 mutations are important for leukemic transformation in murine models of precursor-T leukemia/lymphoma
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Notch promotes survival of pre-T cells at the beta-selection checkpoint by regulating cellular metabolism
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TAL1/SCL induces leukemia by inhibiting the transcriptional activity of E47/HEB
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