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Hui Xu et al.
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The indoleamine 2,3-dioxygenase pathway is essential for human plasmacytoid dendritic cell-induced adaptive T regulatory cell generation
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Prostaglandin E2 is a key factor for monocyte-derived dendritic cell maturation:: enhanced T cell stimulatory capacity despite IDO
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IDO expands human CD4+CD25high regulatory T cells by promoting maturation of LPS-treated dendritic cells
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EUROPEAN JOURNAL OF IMMUNOLOGY (2007)
Induction of FOXP3 expression in naive human CD4+FOXP3- T cells by T-cell receptor stimulation is transforming growth factor-β-dependent but does not confer a regulatory phenotype
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Modulation of tryptophan catabolism by human leukemic cells results in the conversion of CD25- into CD25+ T regulatory cells
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Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production
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IFN-γ mediates CD4+ T-cell loss and impairs secondary antitumor responses after successful initial immunotherapy
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The role of indoleamine 2,3-dioxygenase in transplantation
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Commentary: On watching the watchers: IDO and type I/II IFN
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The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor ζ-chain and induce a regulatory phenotype in naive T cells
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JOURNAL OF IMMUNOLOGY (2006)
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Essay - Dendritic cells in a mature age
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Semi-mature IL-12 secreting dendritic cells present exogenous antigen to trigger cytolytic immune responses
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CANCER IMMUNOLOGY IMMUNOTHERAPY (2005)
Monocyte-mediated T-cell suppression and augmented monocyte tryptophan catabolism after human hematopoietic stem-cell transplantation
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Regulation of human auto- and alloreactive T cells by indoleamine 2,3-dioxygenase (IDO)-prodpcing dendritic cells: too much ado about IDO?
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BLOOD (2005)
Dendritic cells have the option to express IDO-mediated suppression or not
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BLOOD (2005)
Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy
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NATURE MEDICINE (2005)
Ligation of B7-1/B7-2 by human CD4+ T cells triggers indoleamine 2,3-dioxygenase activity in dendritic cells
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A defect in tryptophan catabolism impairs tolerance in nonobese diabetic mice
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JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Tolerance, DCs and tryptophan: much ado about IDO
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SCIENCE (2002)
Inhibition of allogeneic T cell proliferation by indoleamine 2,3-dioxygenase-expressing dendritic cells:: Mediation of suppression by tryptophan metabolites
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JOURNAL OF EXPERIMENTAL MEDICINE (2002)
Defective T-helper cell function after T-cell-depleting therapy affecting naive and memory populations
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BLOOD (2002)
Ex vivo isolation and characterization of CD4+CD25+ T cells with regulatory properties from human blood
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JOURNAL OF EXPERIMENTAL MEDICINE (2001)
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NATURE IMMUNOLOGY (2000)
Indoleamine 2,3-dioxygenase production by human dendritic cells results in the inhibition of T cell proliferation
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JOURNAL OF IMMUNOLOGY (2000)