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A thymic pathway of mouse natural killer cell development characterized by expression of GATA-3 and CD127
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The requirement for Notch signaling at the β-selection checkpoint in vivo is absolute and independent of the pre-T cell receptor
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Notch/Delta signaling constrains reengineering of pro-T cells by PU.1
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Critical role for c-kit (CD117) in T cell lineage commitment and early thymocyte development in vitro
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Prethymic T-cell development defined by the expression of paired immunoglobulin-like receptors
K Masuda et al.
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Hematopoietic stem cell fate is established by the Notch-Runx pathway
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Coordinate analysis of murine immune cell surface markers and intracellular phosphoproteins by flow cytometry
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Notch signaling controls the generation and differentiation of early T lineage progenitors
A Sambandam et al.
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Genetic evidence supporting selection of the Vα14i NKT cell lineage from double-positive thymocyte precursors
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Density of the Notch ligand Delta1 determines generation of B and T cell precursors from hematopoietic stem cells
MH Dallas et al.
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Delayed, asynchronous, and reversible T-lineage specification induced by Notch/Delta signaling
TN Taghon et al.
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The role of Notch and IL-7 signaling in early thymocyte proliferation and differentiation
G Balciunaite et al.
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RBPjκ-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells
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Stat5 tetramer formation is associated with leukemogenesis
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Thymocytes between the β-selection and positive selection checkpoints are nonresponsive to IL-7 as assessed by STAT-5 phosphorylation
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Critical role for Kit-mediated Src kinase but not PI 3-kinase signaling in pro T and pro B cell development
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AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis
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Maintenance of T cell specification and differentiation requires recurrent notch receptor-ligand interactions
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Identification of probabilistic transcriptional switches in the Ly49 gene cluster:: A eukaryotic mechanism for selective gene activation
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Cytokines and immunodeficiency diseases:: critical roles of the γc-dependent cytokines interleukins 2, 4, 7, 9, 15, and 21, and their signaling pathways
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The Ets-1 transcription factor is required for complete pre-T cell receptor function and allelic exclusion at the T cell receptor β locus
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Core-binding factors in hematopoiesis and immune function
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Notch signaling augments T cell responsiveness by enhancing CD25 expression
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Notch1 but not Notch2 is essential for generating hematopoietic stem cells from endothelial cells
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Redundant functions of TCF-1 and LEF-1 during T and NK cell development, but unique role of TCF-1 for Ly49 NK cell receptor acquisition
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Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro
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Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development
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The ETS protein MEF plays a critical role in perforin gene expression and the development of natural killer and NK-T cells
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Inducible gene knockout of transcription factor recombination signal binding protein-J reveals its essential role in T versus B lineage decision
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Vertebrate hairy and Enhancer of split related proteins: transcriptional repressors regulating cellular differentiation and embryonic patterning
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Haploinsufficiency of AML1 affects the temporal and spatial generation of hematopoietic stem cells in the mouse embryo
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Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by Notch1
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Notch1 signaling promotes the maturation of CD4 and CD8 SP thymocytes
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Specification of Drosophila hematopoietic lineage by conserved transcription factors
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The AML1 transcription factor functions to develop and maintain hematogenic precursor cells in the embryonic aorta-gonad-mesonephros region
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The mammalian basic helix loop helix protein HES-1 binds to and modulates the transactivating function of the Runt-related factor Cbfa1
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