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Kathryn A. McMahon et al.
CELL STEM CELL (2007)
Unique and independent roles for MLL in adult hematopoietic stem cells and progenitors
Craig D. Jude et al.
CELL STEM CELL (2007)
Interaction of MLL amino terminal sequences with menin is required for transformation
Corrado Caslini et al.
CANCER RESEARCH (2007)
Deletion of the developmentallv essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss
Yaroslava Ruzankina et al.
CELL STEM CELL (2007)
Distribution of menin-occupied regions in chromatin specifies a broad role of menin in transcriptional regulation
Sunita K. Agarwal et al.
NEOPLASIA (2007)
Mutation of tumor suppressor gene menl acutely enhances proliferation of pancreatic islet cells
Robert W. Schnepp et al.
CANCER RESEARCH (2006)
Genome-wide analysis of menin binding provides insights into MEN1 tumorigenesis
Peter C. Scacheri et al.
PLOS GENETICS (2006)
The tumor suppressor menin regulates hematopoiesis and myeloid transformation by influencing Hox gene expression
YX Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Loss of expression of the Hoxa-9 homeobox gene impairs the proliferation and repopulating ability of hematopoietic stem cells
HJ Lawrence et al.
BLOOD (2005)
The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis
A Yokoyama et al.
CELL (2005)
SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells
MJ Kiel et al.
CELL (2005)
Leukemic transformation of hematopoietic progenitors by MLL-GAS7 in the absence of Hoxa7 or Hoxa9
CW So et al.
BLOOD (2004)
Definitive hematopoiesis requires the mixed-lineage leukemia gene
P Ernst et al.
DEVELOPMENTAL CELL (2004)
Menin associates with a trithorax family histone methyltransferase complex and with the Hoxc8 locus
CM Hughes et al.
MOLECULAR CELL (2004)
MLL: a histone methyltransferase disrupted in leukemia
JL Hess
TRENDS IN MOLECULAR MEDICINE (2004)
Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression
A Yokoyama et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Hoxa9 and Meis1 are key targets for MLL-ENL-mediated cellular immortalization
BB Zeisig et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9
PM Ayton et al.
GENES & DEVELOPMENT (2003)
The decline in B lymphopoiesis in aged mice reflects loss of very early B-lineage precursors
JP Miller et al.
JOURNAL OF IMMUNOLOGY (2003)
Of mice and MEN1: Insulinomas in a conditional mouse knockout
JS Crabtree et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells
IK Park et al.
NATURE (2003)
Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells
J Lessard et al.
NATURE (2003)
Genetic ablation of the tumor suppresor menin causes lethality at mid-gestation with defects in multiple organs
P Bertolino et al.
MECHANISMS OF DEVELOPMENT (2003)
MLL targets SET domain methyltransferase activity to Hox gene promoters
TA Milne et al.
MOLECULAR CELL (2002)
A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
K Akashi et al.
NATURE (2000)