Pregnancy and childbirth outcomes among adolescent mothers: a World Health Organization multicountry study

ObjectiveTo investigate the risk of adverse pregnancy outcomes among adolescents in 29 countries. DesignSecondary analysis using facility-based cross-sectional data of the World Health Organization Multicountry Survey on Maternal and Newborn Health. SettingTwenty-nine countries in Africa, Latin America, Asia and the Middle East. PopulationWomen admitted for delivery in 359 health facilities during 2-4months between 2010 and 2011. MethodsMultilevel logistic regression models were used to estimate the association between young maternal age and adverse pregnancy outcomes. Main outcome measuresRisk of adverse pregnancy outcomes among adolescent mothers. ResultsA total of 124446 mothers aged 24years and their infants were analysed. Compared with mothers aged 20-24years, adolescent mothers aged 10-19years had higher risks of eclampsia, puerperal endometritis, systemic infections, low birthweight, preterm delivery and severe neonatal conditions. The increased risk of intra-hospital early neonatal death among infants born to adolescent mothers was reduced and statistically insignificant after adjustment for gestational age and birthweight, in addition to maternal characteristics, mode of delivery and congenital malformation. The coverage of prophylactic uterotonics, prophylactic antibiotics for caesarean section and antenatal corticosteroids for preterm delivery at 26-34weeks was significantly lower among adolescent mothers. ConclusionsAdolescent pregnancy was associated with higher risks of adverse pregnancy outcomes. Pregnancy prevention strategies and the improvement of healthcare interventions are crucial to reduce adverse pregnancy outcomes among adolescent women in low- and middle-income countries.