Graphene oxide-MnO2 nanocomposite-modified glassy carbon electrode as an efficient sensor for H2O2

In this study, a new facile preparation method of nanocomposites consisting of graphene oxide and manganese dioxide nanowires (GO/MnO2 NWs) was developed. The morphology, structure and composition of the resulted products were characterized by transmission electron microscopy, X-ray diffraction and N-2 adsorption and desorption. The GO/MnO2 nanocomposite was used as an electrode material for non-enzymatic determination of hydrogen peroxide. The proposed sensor exhibits excellent electrocatalytic performance for the determination of hydrogen peroxide in phosphate buffer solution (PBS, pH 7) at an applied potential of 0.75 V. The non-enzymatic biosensor for determination of hydrogen peroxide displayed a wide linear range of 4.90 mu mol L-1 -4.50 mmol L-1 with a correlation coefficient of 0.9992, a low detection limit of 0.48 mu mol L-1 and a high sensitivity of 191.22 mu A (mmol L-1)(-1), cm(-2) (signal/noise, SiN similar or equal to 3). Moreover, the non-enzymatic biosensor shows an excellent selectivity. (C) 2016 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.