4.6 Article

Fungal Recognition and Host Defense Mechanisms

期刊

MICROBIOLOGY SPECTRUM
卷 5, 期 4, 页码 -

出版社

AMER SOC MICROBIOLOGY
DOI: 10.1128/microbiolspec.FUNK-0050-2016

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资金

  1. Wellcome Trust
  2. Medical Research Council Centre for Medical Mycology
  3. University of Aberdeen
  4. Medical Research Council [MR/N006364/1] Funding Source: researchfish
  5. Wellcome Trust [102705/Z/13/Z] Funding Source: researchfish
  6. MRC [MR/N006364/1] Funding Source: UKRI

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Fungi have emerged as premier opportunistic microbes of the 21st century, having a considerable impact on human morbidity and mortality. The huge increase in incidence of these diseases is largely due to the HIV pandemic and use of immunosuppressive therapies, underscoring the importance of the immune system in defense against fungi. This article will address how the mammalian immune system recognizes and mounts a defense against medically relevant fungal species.

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