期刊
CHEMICAL RECORD
卷 17, 期 10, 页码 994-1018出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/tcr.201600140
关键词
asymmetric synthesis; cascade reaction; hydrogen bond; Michael addition; Mannich reaction; organocatalysis squaramides
资金
- National Natural Science Foundation of China (NSFC) [21272024]
Bifunctional squaramides have emerged as powerful hydrogen-bonding catalysts for promoting a wide array of useful asymmetric reactions, which provides convenient methods for the construction of complex molecular structures and chiral biologically active compounds. This review highlights the recent advances of our research group in the chiral squaramide-catalyzed asymmetric reactions, including Michael addition, Mannich reaction, aza-Henry reaction, Strecker reaction as well as cascade or sequential reactions.
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