期刊
BIOTECHNOLOGY FOR BIOFUELS
卷 6, 期 -, 页码 -出版社
BMC
DOI: 10.1186/1754-6834-6-177
关键词
Cellulase; Secretory pathway; Subcellular location; Secretory mechanism; UniProtKB
资金
- Guangxi Science Foundation [12237022, 1347004-1, 2013GXNSDA019007, 13-051-08, 13-051-50]
- BaGui Scholars Program Foundation
Cellulase plays an important role in modern industry and holds great potential in biofuel production. Many different types of organisms produce cellulase, which go through secretory pathways to reach the extracellular space, where enzymatic reactions take place. Secretory pathways in various cells have been the focus of many research fields; however, there are few studies on secretory pathways of cellulases in the literature. It is therefore necessary and important to review the current knowledge on the secretory pathways of cellulases. In this mini-review, we address the subcellular locations of cellulases in different organisms, discuss the secretory pathways of cellulases in different organisms, and examine the secretory mechanisms of cellulases. These sections start with a description of general secreted proteins, advance to the situation of cellulases, and end with the knowledge of cellulases, as documented in UniProt Knowledgebase (UniProtKB). Finally, gaps in existing knowledge are highlighted, which may shed light on future studies for biofuel engineering.
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