期刊
BIOTECHNOLOGY ADVANCES
卷 31, 期 8, 页码 1695-1706出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.biotechadv.2013.08.015
关键词
Gene therapy; Bone; Tissue engineering; Stem cell; Regenerative medicine; Viral vectors; Gene delivery approach
资金
- National Tsing Hua University (Toward World-Class University Project) [102N2051E1]
- CGMH-NTHU Joint Research Program [102N2766E1, 100N7753E1, 101N2753E1, CMR PG3B1541, CMRPG3B0431]
- CGMH Intramural Project [CMRPG300161, CMRPG391721]
- National Science Council, Taiwan [101-2628-E-007-009-MY3, 101-2325-B-080-001, 101-2923-E-007-002-MY3, 99-2221-E-007-025-MY3]
Gene therapy has converged with bone engineering over the past decade, by which a variety of therapeutic genes have been delivered to stimulate bone repair. These genes can be administered via in vivo or ex vivo approach using either viral or nonviral vectors. This article reviews the fundamental aspects and recent progresses in the gene therapy-based bone engineering, with emphasis on the new genes, viral vectors and gene delivery approaches. (C) 2013 Elsevier Inc. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据