期刊
BIOTECHNOLOGY ADVANCES
卷 30, 期 6, 页码 1673-1684出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.biotechadv.2012.07.005
关键词
Dinoflagellates; Microalgae; Marine toxins; Shear-sensitivity; Photobioreactor
资金
- Spanish Ministry of Science and Innovation [SAF2011-28883-C03-02]
- European Regional Development Fund Program
Dinoflagellate microalgae are an important source of marine biotoxins. Bioactives from dinoflagellates are attracting increasing attention because of their impact on the safety of seafood and potential uses in biomedical, toxicological and pharmacological research. Here we review the potential applications of dinoflagellate toxins and the methods for producing them. Only sparing quantities of dinoflagellate toxins are generally available and this hinders bioactivity characterization and evaluation in possible applications. Approaches to production of increased quantities of dinoflagellate bioactives are discussed. Although many dinoflagellates are fragile and grow slowly, controlled culture in bioreactors appears to be generally suitable for producing many of the metabolites of interest. (c) 2012 Elsevier Inc. All rights reserved.
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