期刊
CHINESE JOURNAL OF ORGANIC CHEMISTRY
卷 38, 期 11, 页码 2927-2936出版社
SCIENCE PRESS
DOI: 10.6023/cjoc201805042
关键词
chiral sensor; chiral compound; chiral recognition; enantiomeric excess; absolute configuration
资金
- Chinese Academy of Medical Sciences (CAMS) Innovation Fund for Medical Sciences [2016-I2M-3-009]
Chiral compounds play an essential role in asymmetric synthesis, biology, medical field and pharmacology. It is necessary to establish fast, sensitive and high enantioselective chiral analysis methods. Chiral sensors, which could determine the absolute configuration and the value of enantiomeric excess of enantiomers, have the advantages of simple, rapid. sensitive and real-time. Herein, the review is focused on the recent progress of chiral fluorescent sensors, circular dichroism sensors, Uv-vis sensors, NMR sensors and MS sensors. Their characteristics, sensing mechanism and applications in chiral recognition are reviewed, and the prospects of chiral sensors are also discussed.
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