期刊
BIOSYSTEMS
卷 124, 期 -, 页码 46-60出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.biosystems.2014.08.004
关键词
HIV/AIDS; HCV; Coinfection; Mathematical model
资金
- European Regional Development Fund through the program COMPETE
- Portuguese Government through the FCT - Fundacao para a Ciencia e a Tecnologia [PEst-C/MAT/UI0144/2013]
- FCT [SFRH/BD/96816/2013]
- Fundac ao Gulbenkian, through Premio Gulbenkian de Apoio a Investigac ao
- Polytechnic of Porto, through the PAPRE Programa de Apoio a Publicac ao em Revistas Cientificas de Elevada Qualidade
We study a mathematical model for the human immunodeficiency virus (HIV) and hepatites C virus (HCV) coinfection. The model predicts four distinct equilibria: the disease free, the HIV endemic, the HCV endemic, and the full endemic equilibria. The local and global stability of the disease free equilibrium was calculated for the full model and the HIV and HCV submodels. We present numerical simulations of the full model where the distinct equilibria can be observed. We show simulations of the qualitative changes of the dynamical behavior of the full model for variation of relevant parameters. From the results of the model, we infer possible measures that could be implemented in order to reduce the number of infected individuals. (C) 2014 Elsevier Ireland Ltd. All rights reserved.
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