期刊
BIOSYSTEMS
卷 102, 期 1, 页码 49-54出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.biosystems.2010.07.012
关键词
Silencing; Bistability; Epigenetics
资金
- NHGRI NIH HHS [R01 HG03470-02, R01 HG003470-03, R01 HG003470] Funding Source: Medline
Current biological models of epigenetic switches built on chromatin modifications lead to strong constraints on the repertoire of dynamic behaviors for the system. We use the structure of the bifurcation diagram of the underlying dynamical system to explain the existing single cell data in silencing by the SIR system in yeast. (C) 2010 Elsevier Ireland Ltd. All rights reserved.
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