期刊
BIOSENSORS & BIOELECTRONICS
卷 55, 期 -, 页码 272-277出版社
ELSEVIER ADVANCED TECHNOLOGY
DOI: 10.1016/j.bios.2013.11.081
关键词
Electrochemical sensor; Copper-catalyzed cysteamine oxidation; Silver nanoparticles; Gold nanoparticles; Carbon nanotubes
类别
资金
- National Special Project for Key Scientific Apparatus Development [2012YQ170000302]
- National Basic Research Program [2010CB732400]
- National Natural Science Foundation of China [21105046, 21135002, 21121091]
- PhD Fund for Young Teachers [20110091120012]
- Natural Science Foundation of Jiangsu [BK2011552]
A highly sensitive and selective electrochemical sensor was developed for the detection of Cu2+ by the assembly of Ag nanoparticles (AgNPs) at dithiobis[succinimidylpropionate] encapsulated Au nanopartides (DSP-AuNPs), which was regulated by copper-catalyzed oxidation of cysteamine (Cys). The electrochemical sensor was constructed by layer-by-layer modification of glassy carbon electrode with carbon nanotubes, poly(amidoamine) dendrimers and DSP-AuNPs. In the absence of Cu2+ Cys could bind to the surface of citrate-stabilized AgNPs via Ag-S bond, thus AgNPs could be assembled on the sensor surface through the reaction between DSP and Cys. In contrast, the copper-catalyzed oxidation of Cys by dissolved oxygen in the presence of Cu2+ inhibited the Cys-induced aggregation of AgNPs, leading to the decrease of the electrochemical stripping signal of AgNPs. Under the optimized conditions, this method could detect Cu2+ in the range of 1.0-1000 nM with a detection limit of 0.48 nM. The proposed Cu2+ sensor showed good reproducibility, stability and selectivity. It has been satisfactorily applied to determine Cu2 in water samples. (C) 2013 Elsevier B.V. All rights reserved.
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