期刊
BIOSENSORS & BIOELECTRONICS
卷 60, 期 -, 页码 1-7出版社
ELSEVIER ADVANCED TECHNOLOGY
DOI: 10.1016/j.bios.2014.03.055
关键词
Glutathione; Piroxicam; Biosensor; Voltammetry; FePt/CNTs
类别
资金
- Graduate University of Advanced Technology, Kerman, Iran
This study describes the development, electrochemical characterization and utilization of novel modified N-(4-hydroxyphenyl)-3,5-dinitrobenzamide-FePt/CNTs carbon paste electrode for the electrocatalytic determination of glutathione (GSH) in the presence of piroxicam (PXM) for the first time. The synthesized nanocomposite was characterized with different methods such as TEM and XRD. The modified electrode exhibited a potent and persistent electron mediating behavior followed by well-separated oxidation peaks of GSH and PXM. The peak currents were linearly dependent on GSH and PXM concentrations in the range of 0.004-340 and 0.5-550 mu mol L-1, with detection limits of 1.0 nmol L-1 and 0.1 mu mol L-1, respectively. The modified electrode was successfully used for the determination of the analytes in real samples with satisfactory results. (C) 2014 Elsevier B.V. All rights reserved.
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